Thursday, 29 January 2015

Melioidosis

Melioidosis or also as known as Whitmore's disease is an infectious disease caused by Burkholderia pseudomallei which can be found in soil and water. Melioidosis can infect humans or animals. Melioidosis were frequently reported in climate area especially in  SEA (South East Asia), North Australia, West Africa and South America. Melioidosis infection commonly involves the lungs and also similar to glander disease, which is passed to humans from infected domestic animals. The bacterium that causes the disease is found in the soil, rice paddies, and stagnant waters of the area. People acquire the disease by inhaling dust contaminated by the bacteria and when the contaminated soil and the infection most commonly occurs during rainy season.

It is very rare for people to get the disease from another person. While a few cases have been documented, contaminated soil and surface water remain the primary way in which people become infected.

Besides humans, many animal species are susceptible to melioidosis such as sheep, goats, swine, horses, cats, dogs and cattle.


  • Symptoms
    • Melioidosis has many range of signs and symptoms and usually can be mistaken for other disease such as tuberculosis or pneumonia.
      • Localized pain or swelling, fever, ulceration, abscess, cough, chest pain, high fever, massive headace, anorexia, respiratory disease, abdominal discomfort, joint pain, muscle tenderness, disorientation, weight loss, stomach or chest pain, muscle or joint pain, headache, seizures.
      • Major risk factors to from Melioidosis 
        • Diabetes
        • Liver disease
        • Thalassemia
        • Chronic Lung disease 
        • Cancer or another immune-suppressing condition other than HIV

Melioidosis were greatly reported in Thailand, Malaysia and Singapore.

Melioidosis can be diagnose with microscopic evaluation of a blood,urine sputum or skin-lesion test sample in the laboratory and blood test is useful to detect early acute cases of melioidosis.

  • Prevention
    • Persons with open skin wounds or diabetes or chronic renal disease should prevent themselves by avoiding contact with soil and standing water.
    • Agricultural workers or health care workers should wear PPE (Personal Protective Equipment) such as boots, gloves, mask to prevent infection through skin and inhalation.

Wednesday, 28 January 2015

Epidermiology Triangle Concept of Leptospirosis


Host
  • Mode of transmission
    • Leptospirosis can effect human by direct or indirectly through exposure of animal urine of the carrier. Genus Leptospira bacteria enter the bloodstream through wounds, cuts, bruised skin and mucus membranes such as eyes, nose and mouth.
    • Also can be spread by the semen of infected animals. Butcher and slaughterer also can be infected through contact with body fluids and blood.
    • Human can be infected through exposure of water, food or soil containing urine from infected animals bacteria. May happen by swallowing contaminated food or water or by contact with the skin.
    • Pets owner can be infected by the dog's saliva if the dog already infected by licking the rodents bacteria.
  • Prevention
    • By not swimming in the contaminated water.
    • Not in contact with animals that have been exposed to infection.
    • Wear PPE or protective clothing or footwear.
    • Frequent medical checkups.
    • Frequent visit to vet clinic for animal vaccine for pets.
    • Antibiotics such as doxycyline and pennicilin.
    • Extra cautions on handling animal's urine or blood.
    • Always wash your hands with anti-bacterial cleaning solution.